“Establishment of companion diagnostics and development of new treatment with cardiac acetylcholine-sensitive K+ channel selective inhibitors for hereditary bradycardia intractable disease (Kir3.1/3.4 channelopathy)”

Item	Content
Research project name	Practical Research Project for Rare / Intractable Diseases
Study title	“Establishment of companion diagnostics and development of new treatment with cardiac acetylcholine-sensitive K+ channel selective inhibitors for hereditary bradycardia intractable disease (Kir3.1/3.4 channelopathy)”
Name of principal investigator	Yoshihiro Asano
Name of institution of the principal investigator	Department of Cardiovascular Medicine, Osaka University Graduate School of Medicine
Target disease	Hereditary bradycardia arrhythmia diseases
Registry name	Registry of hereditary bradycardia arrhythmia diseases
Purpose of registry	Survey of natural history, Investigation into the number or the distribution of patients, Sample collection, Genetic analysis study
Overview of registry	This registry registers clinical information on the prevalence of arrhythmia diseases, prognostic factors, details of treatment and prognosis of the patients who were diagnosed with arrhythmia diseases (atrial fibrillation, atrioventricular block of grade II or higher, sick sinus syndrome, sinus arrest, sinoatrial block, sinus bradycardia and pacemaker implantation), and accumulates genomic information by genomic analysis of the patients upon informed consent.
Research item	Name, Sex, Date of birth, Contact (TEL, FAX, e-mail address, etc.), Information about the current medical institutions of patients, Family history, Past medical history, Complication, History of present illness, History of treatment, Laboratory data, Functional prognosis, Prognosis
Contact	Yoshihiro Asano
E-mail address	asano●cardiology.med.osaka-u.ac.jp
Registry URL

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